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Miki S et al. S-1-Propenylcysteine promotes IL-10-induced M2c macrophage polarization through prolonged activation of IL-10R/STAT3 signaling. Sci Rep. 2021 Nov 17;11(1):22469.
Kunimura K et al. S-1-propenylcysteine improves TNF-α-induced vascular endothelial barrier dysfunction by suppressing the GEF-H1/RhoA/Rac pathway. Cell Commun Signal. 2021; 19: 17.
Ushijima M et al. S-1-Propenylcysteine, a sulfur compound in aged garlic extract, alleviates cold-induced reduction in peripheral blood flow in rat via activation of the AMPK/eNOS/NO pathway Exp Ther Med. 2020 Sep; 20(3):2815-2821.
Matsutomo T Potential benefits of garlic and other dietary supplements for the management of hypertension (Review) Exp Ther Med. 2020; 19(2):1479-1484.
Matsutomo T et al. Metabolomic study reveals the acute hypotensive effect of S-1-propenylcysteine accompanied by alteration of the plasma histidine level in spontaneously hypertensive rats. J Pharm Biomed Anal. 2019 Feb 12; 168:148-154.
Tsuneyoshi T et al. S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells. Nitric Oxide. 2019 Jan 8; 84: 22-29.
Ushijima M et al. Effects of S-1-propenylcysteine, a sulfur compound in aged garlic extract, on blood pressure and peripheral circulation in spontaneously hypertensive rats. J Pharm Pharmacol. 2018 Apr; 70(4): 559-565.
Hiramatsu K et al. Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expressions via Nrf2-ARE pathway in human endothelial cells. Nutrition Research, 2016;36(2):143-9.
Matsutomo T et al. Metabolomic study on the antihypertensive effect of S-1-propenylcysteine in spontaneously hypertensive rats using liquid chromatography coupled with quadrupole-Orbitrap mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:147-155.
Morihara N, Hino A. Aged garlic extract suppresses platelet aggregation by changing the functional property of platelets. J Nat Med. 2017; 71:249-256.
牛島光保. 熟成ニンニク抽出液の末梢循環改善作用. FOOD Style 21. 2017;21(12):75-77.
Takashima M et al. Aged garlic extract exerts endothelium-dependent vasorelaxant effect on rat aorta by increasing nitric oxide production. Phytomedicine. 2017 Jan 15;24:56-61.
Morihara N et al. Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E-Knockout Mice. J Nutr. 2016 Feb;146(2):460S-463S.
Tsuneyoshi T et al. Dehydrodiconiferyl alcohol suppresses monocyte adhesion to endothelial cells by attenuation of JNK signaling pathway. Biochem Biophys Res Commun. 2015 Sep 25; 465(3): 408-13.
Yamakawa T et al. Aged garlic extract and one of the constituent, (+)-(2S,3R)-Dehydrodiconiferyl alcohol, inhibits alkaline phosphatase activity induced by inflammation factors in human vascular smooth muscle cells. Food and Nutrition Science. 2014; 5(2): 177-184.
Weiss N et al. Aged garlic extract restores nitric oxide bioavailability in cultured human endothelial cells even under conditions of homocysteine elevation. J Ethnopharmacol. 2013; 145(1): 162-7.
Morihara N et al. Aged garlic extract inhibits homocysteine-induced scavenger receptor CD36 expression and oxidized low-density lipoprotein cholesterol uptake in human macrophages in vitro. J Ethnopharmacol. 2011; 134(3): 711-6.
Morihara N et al. Aged garlic extract inhibits CD36 expression in human macrophages via modulation of the PPARgamma pathway. Phytother Res. 2010; 24(4): 602-8.
Abahji TN et al. Acute hyperhomocysteinemia induces microvascular and macrovascular endothelial dysfunction. Arch Med Res. 2007; 38(4): 411-6.
Weiss N et al. Aged garlic extract improves homocysteine-induced endothelial dysfunction in macro-and microcirculation. J Nutr. 2006 Mar;136(3 Suppl):750S-754S.
Ide N et al. Aged garlic extract inhibits homocysteine-induced CD36 expression and foam cell formation in human macrophages. J Nutr. 2006 Mar;136(3 Suppl):755S-758S.
Morihara N et al. Aged garlic extract maintains cardiovascular homeostasis in mice and rats. J Nutr. 2006 Mar;136(3 Suppl):777S-781S.
Morihara N et al. Aged garlic extract inhibits peroxynitrite-induced hemolysis. Redox Rep. 2005; 10(3): 159-65.
Budoff MJ et al. Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study. Prev Med. 2004; 39(5): 985-91.
Morihara N et al. Aged garlic extract enhances production of nitric oxide. Life Sci. 2002; 71(5): 509-17.
Ide N, Lau BH. Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-kappa b activation. J Nutr. 2001; 131(3s): 1020S-6S.
Ho SE et al. S-allyl cysteine reduces oxidant load in cells involved in the atherogenic process. Phytomedicine. 2001; 8(1): 39-46.
Matsuura H. Saponins in garlic as modifiers of the risk of cardiovascular disease. J Nutr. 2001; 131(3s): 1000S-5S.
Moriguchi T et al. The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes. J Nutr. 2001; 131(3s): 1016S-9S.
Ide N, Lau BH. Aged garlic extract attenuates intracellular oxidative stress. Phytomedicine. 1999; 6(2): 125-31.
Ide N et al. Antioxidant effects of fructosyl arginine, a Maillard reaction product in aged garlic extract. J Nutr. Biochem. 1999; 10(6): 372-6.
Ide N, Lau BH. S-allylcysteine attenuates oxidative stress in endothelial cells. Drug Dev Ind Pharm. 1999; 25(5): 619-24.
住吉博道. にんにくの抗酸化作用、成人病予防食品の開発. 1999; 91-98. シーエムシー出版.
Ide N et al. Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein. Planta Med. 1997; 63(3): 263-4.
Ide N, Lau BH. Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. J Pharm Pharmacol. 1997; 49(9): 908-11.
山崎毅. にんにく製剤およびにんにく由来イオウ化合物の抗酸化能. 日薬理誌. 1997; 110: 138-141.
Yamasaki T et al. Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury. Phytother Res. 1994; 8: 408-12.
Nakamoto M and Kunimura K. Study of the metabolism of S-allylmercaptocysteine to elucidate its metabolites and metabolic pathway in rats. Eur Food Res Technol. 2023;249:1377-1389.
Amano H et al. Evaluation of the Effects of S-Allyl-L-cysteine, S-Methyl-L-cysteine, trans-S-1-Propenyl-L-cysteine, and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities. Biol. Pharm. Bull. 2016;39(10):1701-1707.
Amano H et al. Pharmacokinetics and N-acetylation metabolism of S-methyl-l-cysteine and trans-S-1-propenyl-l-cysteine in rats and dogs. Xenobiotica. 2016 Nov;46(11):1017-25.
Amano H et al. Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption. J Nutr. 2016 Feb;146(2):456S-459S.
Amano H et al. Metabolism, Excretion, and Pharmacokinetics of S-Allylcysteine in Rats and Dogs. Drug Metabolism and Disposition. 2015; 43(5): 749-755.
Matsutomo T et al. Pharmacokinetics of water soluble organosulfur compounds from garlic. J Clin Biochem Nutr. 2008; 43(supple 1):100-4.
Ichikawa M et al. Pharmacokinetics of cycloalliin, an organosulfur compound found in garlic and onion, in rats. J Agric Food Chem. 2006; 54(26): 9811-9.
Kodera Y et al. Pharmacokinetic study of allixin, a phytoalexin produced by garlic. Chem Pharm Bull (Tokyo). 2002; 50(3): 354-63.
Amagase H. Role of maker compounds of herbs and their bioavailability in quality, efficacy and safety of products. Quality Management of Nutraceuticals, 2001; 803(Chapter 5): 63-75.
吉田進ほか. ニンニクの変異原性試験および細胞毒性試験. J Toxicol Sci. 1984; 9: 77-86
住吉博道ほか. ニンニク抽出液のラットにおける6ヶ月慢性毒性試験. J Toxicol Sci. 1984; 9(1): 61-75.
中川静紀ほか. ニンニク抽出液の急性毒性試験. J Toxicol Sci. 1984;9:57-60.
中川静紀ほか. 生ニンニクおよびニンニク抽出液の経口投与による若年ラットの発育，諸臓器などへの影響. J Toxicol Sci. 1980; 5: 91-112.
Abe K et al. Identification and Characterization of Sulfur Heterocyclic Compounds That Contribute to the Acidic Odor of Aged Garlic Extract. J. Agric. Food Chem. 2021, 69, 3, 1020–1026
Abe K et al. Volatile compounds of fresh and processed garlic (Review) Exp Ther Med. 2020; 19(2):1585-1593.
Kodera Y et al. Chemistry of aged garlic: Diversity of constituents in aged garlic extract and their production mechanisms via the combination of chemical and enzymatic reactions (Review) Exp Ther Med. 2020; 19(2):1574-1584.
Kurita M et al. 3-Allyltrisulfanyl-alanine Formation during the Preparation of Aged Garlic Extract J Agric Food Chem. 2020; 68:14577-83.
Nakamoto M et al. Identification and determination of antibacterial constituents in residue discharged from garlic-processing plant Eur Food Res Technol. 2020; 246:1041-1049.
Myoda T et al. Characterization of key aroma compounds in aged garlic extract Food Chem. 2019 Dec 24; 312: 126081.
Hofmann, T et al. Targeted Screening and Quantitative Analyses of Antioxidant Compounds in Aged Garlic Extract. Eur Food Res Technol. 2018 October; 244(10):1803-1814.
Kodera Y et al. Changes of S-allylmercaptocysteine and γ-glutamyl-S-allylmercaptocysteine contents and their putative production mechanisms in garlic extract during the aging process. J Agric Food Chem. 2018 Sep 18; 66, (40): 10506–10512.
Nakamoto M et al. Isolation and Identification of Three γ-Glutamyl Tripeptides and Their Putative Production Mechanism in Aged Garlic Extract. J Agric Food Chem. 2018 Mar 21;66(11):2891-2899.
Kodera Y et al. Chemical and Biological Properties of S-1-Propenyl-l-Cysteine in Aged Garlic Extract. Molecules. 2017 Mar 31;22(4): 570.
Matsutomo T et al. Development of a fast and sensitive UPLC-MS/MS method for quantitation of dilignols in aged garlic extract. European Food Research and Technology. 2016 Jun; 242(6): 849-854.
Matsutomo T, Kodera Y. Development of an Analytic Method for Sulfur Compounds in Aged Garlic Extract with the Use of a Postcolumn High Performance Liquid Chromatography Method with Sulfur-Specific Detection. J Nutr. 2016 Feb;146(2):450S-455S.
Wakamatsu J et al. Taste-Active Maillard Reaction Products in Roasted Garlic (Allium sativum). J Agric Food Chem. 2016 Jul 27;64(29):5845-54.
Yoshimoto N et al. Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin. Front Plant Sci. 2015 Jan 8; 5: 758.
Kodera Y et al. The Evidence for the Production Mechanism of cis-S-1-Propenylcysteine in Aged Garlic Extract Based on a Model Reaction Approach Using Its Isomers and Deuterated Solvents. Planta Med Lett. 2015; 2(01): e69-e72.
Yoshimoto N et al. Identification of a flavin-containing S-oxygenating monooxygenase involved in alliin biosynthesis in garlic. Plant J. 2015 Sep; 83(6): 941-51.
Matsutomo T et al. In Vitro Activity-Guided Identification of Antioxidants in Aged Garlic Extrac. Journal of Agricultural and Food Chemistry. 2013, 61(12); 3059-3067.
Ichikawa M et al. Changes in organosulfur compounds in garlic cloves during storage. J Agric Food Chem. 2006; 54(13): 4849-54.
Amagase H. Clarifying the real bioactive constituents of garlic. J Nutr. 2006 Mar;136(3 Suppl):716S-725S.
Ichikawa M et al. Determination of seven organosulfur compounds in garlic by high-performance liquid chromatography. J Agric Food Chem. 2006; 54(5): 1535-40.
Ichikawa M et al. Tetrahydro-beta-carboline derivatives in aged garlic extract show antioxidant properties. J Nutr. 2006 Mar;136(3 Suppl):726S-731S.
Ichikawa M et al. Antioxidant effcts of tetrahydro-beta-carboline derivatives identified in aged garlic extract. ACS SYMPOSIUM SERIES 871, Nutraceutical Beverages Chemistry, Nutrition, and Health Effects. 2003; 28: 380-404.
Ide N et al. Antioxidants in Processed Garlic: Tetrahydro-β-carboline derivatives in aged garlic extract. ACS SYMPOSIUM SERIES 851, Food Factors in Health Promotion and Disease Prevention. 2003;22:250-263.
Kodera Y et al. Garlic chemistry: Chemical and biological properties of sulfur-containing compounds derived from garlic. ACS Symposium series 851, Food Factors in Health Promotion and Disease Prevention. 2003;30:346-357.
Ichikawa M et al. Identification of six phenylpropanoids from garlic skin as major antioxidants. J Agric Food Chem. 2003; 51(25): 7313-7.
Ryu K et al. Liquid Chromatography-Mass Spectrometry Method for Fructosylarginine , an Antioxidant in the Aged Garlic Extract. ACS SYMPOSIUM SERIES 851, Food Factors in Health Promotion and Disease Prevention, 2003;23: 264-273.
Ryu K, Rosen RT. Unique Chemistry of Aged Garlic Extract. ACS SYMPOSIUM SERIES 859, Oriental Foods and Herbs. 2003; 19:258-270.
Kodera Y et al. Allixin accumulation with long-term storage of garlic. Chem Pharm Bull (Tokyo). 2002; 50(3): 405-7.
Ichikawa M et al. Antioxidant effects of tetrahydro-beta-carboline derivatives identified in aged garlic extract. Biofactors. 2002; 16(3-4): 57-72.
Ide N et al. Antioxidants in processed garlic Ⅱ. Tetrahydro-beta-carboline derivatives indentified in aged garlic extract. Int Cong Ser. 2002;1245:449-50.
Ide N et al. Antioxidants in processed garlic I. Fructosyl arginine indentified in aged garlic extract. Int Cong Ser. 2002; 1245: 447-8.
Kodera Y et al. Physical, chemical, and biological properties of s-allylcysteine, an amino acid derived from garlic. J Agric Food Chem. 2002; 50(3): 622-32.
Ryu K et al. N alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract. J Nutr. 2001; 131(3s): 972S-6S.
Kodera Y et al. Allixin induction and accumulation by light irradiation. Chem Pharm Bull (Tokyo). 2001; 49(12): 1636-7.
Tsuneyoshi T et al. Differentiation of Allium carlaviruses isolated from different parts of the world based on the viral coat protein sequence. Arch Virol. 1998; 143(6): 1093-107.
Matsumura Y et al. Facile Synthesis of Allixin and Its Related Compounds. Tetrahedron Lett. 1998; 39: 2339-40.
Inagaki M et al. Isolatin and structure determination of cerebrosides from garlic, the bulbs of Allium sativum L. Chem Pharm Bull (Tokyo). 1998; 46: 1153-6.
Kyo E et al. Anti-allergic effects of aged garlic extract. Phytomedicine. 1997; 4(4): 335-40.
住吉博道. ニンニク及びその成分の新しい薬理活性. 日薬理誌.1997; 110 suppl 1:93-97.
Matsuura H et al. Changes in contents of gamma-glutamyl peptides and fructan during growth of Allium sativum. Planta Med. 1996; 62(1): 70-1.
Ide N et al. Scavenging effect of aged garlic extract and its constutuent on active oxygen species. Phytother Res. 1996;10: 340-1.
Freeman F, Kodera Y. Garlic chemistry: Stability of S-(2-Propenyl) 2-Propene-1-sulfinothioate(Allicin)in blood, soｌvents, and simulated physiological fluids. J Agric Food Chem. 1995; 43(9): 2332-8.
Imai J et al. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med. 1994; 60(5): 417-20.
Nagae S et al. Pharmacokinetics of the garlic compound S-allylcysteine. Planta Med. 1994; 60(3): 214-7.
Horie T et al. Identified diallyl polysulfides from an aged garlic extract which protects the membranes from lipid peroxidation. Planta Med. 1992; 58(5): 468-9.
Yamasaki T et al. Effect of allixin, a phytoalexin produced by garlic, on mutagenesis, DNA-binding and metabolism of aflatoxin B1. Cancer Lett. 1991; 59(2): 89-94.
Matsuura H et al. A furostanol glycoside from Allium chinese G. Don. Chem Pharm Bull (Tokyo). 1989; 37(5): 1390-1391.
Kodera Y et al. Allixin, a stress compound from garlic. Chem Pharm Bull (Tokyo). 1989; 37(6): 1656-8.
Matsuura H et al. A furostanol glycoside from garlic, bulbs of Allium sativum L. Chem Pharm Bull (Tokyo). 1988; 36(9): 3659-3663.
Morita T et al. Steroidal saponins from elephant garlic, bulbs of Allium ampeloprasum L. Chem Pharm Bull (Tokyo). 1988; 36(9): 3480-6.
高原征一ほか. ニンニクから得られた脂肪酸エステルによるmonoamine oxidaseの阻害. 栄養と食糧.
Takahashi K et al. Therapeutic effect of aged garlic extract on gingivitis in dogs. Front. Vet. Sci. 2023 Nov;10:1277272
Nango H and Ohtani M. S-1-propenyl-L-cysteine suppresses lipopolysaccharide-induced expression of matrix metalloproteinase-1 through inhibition of tumor necrosis factor-α converting enzyme-epidermal growth factor receptor axis in human gingival fibroblasts. PLoS One. 2023 Apr 21;18(4):e0284713.
Abe K et al. Protective effects of volatile components of aged garlic extract against ultraviolet B-induced apoptosis in human skin fibroblasts. J Food Biochem. 2022 Dec;46(12):e14482.
Nakamoto M et al. Antimicrobial properties of hydrophobic compounds in garlic: Allicin, vinyldithiin, ajoene and diallyl polysulfides (Review) Exp Ther Med. 2020; 19(2):1550-1553.
Ohtani M et al. The preventive and therapeutic application of garlic and other plant ingredients in the treatment of periodontal diseases (Review) Exp Ther Med. 2020; 19(2):1507-1510.
Tsuneyoshi T BACH1 mediates the antioxidant properties of aged garlic extract (Review) Exp Ther Med. 2020; 19(2):1500-1503.
Hofmann, T et al. Antioxidative Maillard Reaction Products Generated in Processed Aged Garlic Extract. J Agric Food Chem. 2019 Feb 27; 67(8):2190-2200.
Yamato O et al. Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes BMC Vet Res. 2018 Nov 29; 14(1):373.
角愼一郎. ニンニクの健康機能～熟成ニンニク抽出液をめぐる最近の話題～. Food Style21. 2002; 6: 47-9.
Ayabe M, Sumi S. A novel and efficient tissue culture method ? "stem-disc dome culture" ? for producing virus-free garlic (Allium sativum L.). Plant Cell Rep. 2001; 20: 503-7.
Sumi S et al. Development and establishment of practical tissue culture methods for production of virus-free garlic seed bulbs, a novel field cultivation system and convenient methods for detecting garlic infecting viruses. Plant biotechnology. 2001 18(3): 179-190.
Amagase H et al. Intake of garlic and its bioactive components. J Nutr. 2001; 131(3s): 955S-62S.
Kajimura Y et al. A new garlic growing system from bulbils through transplanting. J Horticult Sci Biotechnol. 2000; 75(2): 176-80.
Sumi S et al. Complete nucleotide sequences of garlic viruses A and C, members of the newly ratified genus Allexivirus. Arch Virol. 1999; 144(9): 1819-26.
Peteschand BLH, Sumiyoshi H. Recent advances on the nutritional benefits accompanying the use of garlic as a supplement. Trends Food Thechnol. 1999; 9: 415-8.
住吉博道. にんにくによる老化予防、老化予防食品の開発. 吉川敏一監修.1999; 170-177.シーエムシー出版.
春日繁男ほか. 書籍「Medicinal and Aromatic Plants: Genus Allium 」の分筆. Medicinal and Aromatic Plants.
Ayabe M, Sumi S. Establishment of novel tissue culture method, stem-disc culture, and its practical application to micropropagation of garlic (Alliun Sativum L). Plant Cell Rep. 1998; 17: 773-9.
Tsuneyoshi T et al. Nucleotide sequence analysis of virus isolates indicates the presence of three potyvirus species in Allium plants. Arch Virol. 1998; 143(1): 97-113.
Tsuneyoshi T et al. Nucleotide sequences of the 3' terminal region of onion yellow dwarf virus isolates from Allium plants in Japan. Virus Genes. 1997; 15(1): 73-7.
Amagase H et al. Dietary components modify the ability of garlic to suppress 7,12-dimethylbenz(a)anthracene-induced mammary DNA adducts. J Nutr. 1996; 126(4): 817-24.
Tsuneyoshi T, Sumi S. Differentiation among garlic viruses in mixed infections based on RT-PCR procedures and direct tissue blotting immunoassays. Phytopathol. 1996; 86: 253-9.
Ayabe M et al. Regeneration of whole plants from protoplasts isolated from tissue-cultured shoot primordia of garlic (Allium sativum L.). Plant Cell Rep. 1996; 15(1-2): 17-21.
角愼一郎. ニンニクの茎盤部培養. 備北バイオの里. 1995; 11: 1-2.
Sumi S et al. Novel rod-shaped viruses isolated from garlic, Allium sativum, possessing a unique genome organization. J Gen Virol. 1993;74 ( Pt 9): 1879-85.
Lau BHS et al. Edible extracts modulate macrophage activity and bacterial mutagenesis. Clin Nutr Rev. 1992;12(3): 147-55.
Sugimoto H et al. Embryo-cultured hybrids between garlic and leek. Allium Improvement Newsletter. 1991;1: 67-8.
綾部昌則. ニンニクの誘導法. バイオホルティ. 1990;6:28-9.
Matsuura H et al. Further studies on steroidal glycoside from bulbs, roots and leaves of Allium sativum L. Chem Pharm Bull (Tokyo). 1989; 37(10): 2741-2743.
Horie T et al. Protection of liver microsomal membranes from lipid peroxidation by garlic extract. Planta Med. 1989; 55(6): 506-8.
Yoshida S et al. Nakagawa S. Antifungal activity of ajoene derived from garlic. Appl Environ Microbiol. 1987; 53(3): 615-7.
Kasuga S et al. Morphological observations of rabbit gastric fundus cells in primary culture. Hiroshima J Med Sci. 1987; 36(3): 283-7.
今村和彦. 麹菌の新たな機能性. 生物工学会誌. 2015;93(8): 491.
樋口雅治ほか. Hygroscopicity of a sugarless coating layer formed by the interaction between mannitol and poly(vinyl alcohol) (PVA). Colloids Surf B Biointerfaces. 2014 Nov 1;123:557-65.
Moriguchi T et al. Plasticity of mouse brain docosahexaenoic acid: modulation by diet and age. Lipids. 2013; 48(4): 343-55.
Imamura K et al. Identification of a gene involved in the synthesis of a dipeptidyl peptidase IV inhibitor in Aspergillus oryzae. Appl Environ Microbiol. 2012 Oct;78(19):6996-7002.
Higashikawa F et al. Reduction of serum lipids by the intake of the extract of garlic fermented with Monascus pilosus: a randomized, double-blind, placebo-controlled clinical trial. Clin Nutr. 2012; 31(2): 261-6.
Imamura K et al. Identification of a gene involved in the synthesis of a dipeptidyl peptidase IV inhibitor in Aspergillus oryzae. Appl Environ Microbiol. 2012; 78(19): 6996-7002.
Sakata Y, Yamaguchi H. Effects of calcium salts on thermal characteristics of hydroxypropyl methylcellulose films Journal of Non-Crystalline Solids. 2011; 357, (4): 1279-1284.
Sakata Y, Yamaguchi H. Improvement of sticking in tablet compaction for tocopherol acetate. Drug Dev Ind Pharm. 2011; 37(9): 1049-59.
Iguchi K et al. Castration- and aging-induced changes in the expression of zinc transporter and metallothionein in rat prostate. J Androl. 2011; 32(2): 144-50.
Imamura K et al. Identification and characterization of a novel fermented substance produced by edible Aspergillus oryzae AO-1 that inhibits DPP-IV activity. J Biosci Bioeng. 2011 Jan;111(1):37-40.
Harauma A et al. Repletion of n-3 fatty acid deficient dams with alpha-linolenic acid: effects on fetal brain and liver fatty acid composition. Lipids. 2010; 45(8): 659-68.
Komoto N et al. Murine metabolism and absorption of lancemaside A, an active compound in the roots of Codonopsis lanceolata. J Nat Med. 2010; 64(3): 321-9.
Shiraishi S et al. Practical application to indicator time of a novel white film formed by intraction of calcium salts with hydroxypropyl methylcellulose. Int J Pharm. 2010 Jan 4;383(1-2):255-6.
Yamakawa T et al. Modulator Recognition Factor-2 regulates Triglyceride Metabolism in Adipocytes. Biochem Biophys Res Commun. 2010 Jan 1;391(1):277-81.
岡孝己ほか. 膵臓内分泌細胞の分化とホルモン分泌を調節する新規分子の発見とその作用機序の解明. 薬学雑誌. 2010;130(3):377-388.
Mohri Y et al. Quantitative evaluation of glycyrrhizic acid that affects the product quality of Kakkonto extract, a traditional herbal medicine, by a chemometric near infrared spectroscopic method. J Near Infrared Spectrosc. 2009; 17(2): 89-100.
Sakata Y, Otsuka M. Evaluation of relationship between molecular behaviour and mechanical strength of pullulan films. Int J Pharm. 2009 5; 374(1-2): 33-8.
池田陽一. 添加剤における処方例-徐放剤・可溶化剤-. 書籍【医薬品/化粧品/医薬部外品】対応-添加剤の選定活用と規制/申請対応. 2008; 技術情報協会.
Kanou S et al. Effect of dehydration and urea on stability of homosulfamine in solid states. Drug Dev Ind Pharm. 2008; 34(7): 771-80.
Yamashiro J et al. Dimerumic acid protected oxidative stress-induced cytotoxicity in isolated rat hepatocytes. Cell Biol Toxicol. 2008; 24(4): 283-90.
Yamakawa T et al. Modulator recognition factor-2 is required for adipogenesis in mouse embryo fibroblasts and 3T3-L1 cells. Mol Endocrinol. 2008; 22(2): 441-53.
Ushijima M et al. Codonopsis lanceolata accelerates recovery from the reproductive dysfunction induced by hyperthermic treatment in male mice. 応用薬理. 2008; 75(3/4): 63-8.
Ushijima M et al. Codonopsis lanceolata improves a plasma testosterone deficiency induced by immobilization stress in male mice. 応用薬理. 2008; 75(3/4): 69-75.
Ushijima M et al. Triterpene glycosides from the roots of Codonopsis lanceolata. Chem Pharm Bull (Tokyo). 2008; 56(3): 308-14.
Ichikawa M et al. Rapid identification of triterpenoid saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry. J Nat Med. 2008; 62(4): 423-9.
Shirota O et al. Preparative separation of the saponin lancemaside a from Codonopsis lanceolata by centrifugal partition chromatography. Phytochem Anal. 2008;19(5): 403-10.
鈴木直人ほか. 軟カプセル剤の崩壊遅延防止技術「F-CAPS」について. 食品機械装置. 2008;4.
Ichikawa M et al. Simultaneous determination of seven saponins in the roots of Codonopsis lanceolata by liquid chromatography-mass spectrometry. J Nat Med. 2009; 63(1): 52-7.
Sakata Y et al. Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations. Int J Pharm. 2007; 335(1-2): 12-9.
Nishimura Ka et al. Improvement of Dispersion and Release Properties of Nifedipine in Suppositories by Complexation with 2-Hydroxypropyl-β-cyclodextrin. J Incl Phenom Macrocycl Chem. 2006; 56: 85-88.
Sakata Y et al. A novel white film for pharmaceutical coating formed by interaction of calcium lactate pentahydrate with hydroxypropyl methylcellulose. Int J Pharm. 2006; 317(2): 120-6.
Sakata Y et al. Effect of pulverization and dehydration on the pharmaceutical properties of calcium lactate pentahydrate tablets. Colloids Surf B Biointerfaces. 2006; 51(2): 149-56.
守口徹. 総説：n-3系脂肪酸、特にDHAの吸収・消失に関する研究. 日本脂質栄養学会誌. 2006;15(1),85-92.
鈴木直人ほか. 軟カプセル剤の崩壊遅延防止技術「F-CAPS」. 製剤機械技術研究会誌. 2006; 15(3): 17-23.
Sumioka I et al. Lipid-lowering effect of monascus garlic fermented extract (MGFE) in hyperlipidemic subjects. Hiroshima J Med Sci. 2006; 55(2): 59-64.
Sakata Y et al. Effect of tablet geometrical structure on the dehydration of creatine monohydrate tablets, and their pharmaceutical properties. AAPS PharmSciTech. 2005; 6(3): E527-35.
Ichikawa M et al. Effect of various halide salts on the incompatibility of cyanocobalamin and ascorbic acid in aqueous solution. Chem Pharm Bull. 2005; 53(6): 688-90.
Sakata Y et al. Effect of pulverization of the bulk powder on the hydration of creatine anhydrate tablets and their pharmaceutical properties. Colloids Surf B Biointerfaces. 2005; 46(2): 92-100.
Sakata Y et al. Characterization of dehydration and hydration behavior of calcium lactate pentahydrate and its anhydrate. Colloids Surf B Biointerfaces. 2005; 46(3): 135-41.
下川義之. 生薬(天然物)を含有する軟カプセル剤の不溶化防止. Pharm Tech Jpn. 2004; 20(12): 2379-84,2387-9.
Ikeda Y et al. Potential use of 2-hydroxypropyl-β-cyclodextrin as a release modifier of a water-soluble drug, metoprolol tartrate, from ethylcellulose tablets. J Drug Del. Sci Tech. 2004; 14(1): 69-76.
Sumioka I et al. Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury. Life Sci. 2004; 74(20): 2551-61.
Ikeda Y et al. NMR spectroscopic characterization of metoprolol/cyclodextrin complexes in aqueous solution: cavity size dependency. J Pharm Sci. 2004; 93(7): 1659-71.
Sakata Y et al. Characterization of dehydration behavior of untreated and pulverized creatine monohydrate powders. Colloids Surf B Biointerfaces. 2004; 35(3-4): 185-91.
Sumioka I et al. Acetaminophen-induced hepatotoxicity: Still an important issue. Yonago Acta Med. 2004; 47: 17-28.
Sakata Y et al. Effect of pulverization on hydration kinetic behaviors of creatine anhydrate powders. Colloids Surf B Biointerfaces. 2004; 39(4): 187-93.
門間正子ほか. 定期試験における男子学生の免疫機能に関する検討. 札幌医科大学保健医療学部紀要. 2002;(5): 45-50.
井瀧千恵子ほか. 看護学生の臨地実習後の感情とNK細胞活性に関する検討. 札幌医科大学保健医療学部紀要. 2002; 5: 51-5.
Murthy M et al. Differential effects of n-3 fatty acid deficiency on phospholipid molecular species composition in the rat hippocampus. J Lipid Res. 2002; 43(4): 611-7.
Ahmad A et al. Salem N Jr. A decrease in cell size accompanies a loss of docosahexaenoate in the rat hippocampus. Nutr Neurosci. 2002; 5(2): 103-13.
Ahmad A et al. Decrease in neuron size in docosahexaenoic acid-deficient brain. Pediatr Neurol. 2002; 26(3): 210-8.
Ikeda Y et al. Inclusion complex formation of captopril with alpha- and beta-cyclodextrins in aqueous solution: NMR spectroscopic and molecular dynamic studies. J Pharm Sci. 2002; 91(11): 2390-8.
Ikeda Y et al. Effect of 2-Hydroxypropyl-β-cyclodextrin on Release Rate of Metoprolol from Ternary Metoprolol/2-hydroxypropyl-β-cyclodextrin/Ethylcellulose Tablets. J Incl Phenom Macro Chem. 2002; 44: 141-4.
Tsuchida A et al. The effects of brain-derived neurotrophic factor on insulin signal transduction in the liver of diabetic mice. Diabetologia. 2001; 44(5): 555-66.
佐竹元吉ほか. 薬用植物の開発研究 (ヒューマンサイエンス振興財団S) 創薬等ヒューマンサイエンス研究総合研究報告書. 平成10-12年度 第5分野 健康保持増進・予防医薬品の開発に関する研究. 2001; p86-99.
Greiner RS et al. Olfactory discrimination deficits in n-3 fatty acid-deficient rats. Physiol Behav. 2001; 72(3): 379-85.
Nishio H et al. Prenatal stress and postnatal development of neonatal rats--sex-dependent effects on emotional behavior and learning ability of neonatal rats. Int J Dev Neurosci. 2001; 19(1): 37-45.
Moriguchi T et al. Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum. J Lipid Res. 2001; 42(3): 419-27.
Yamada M et al. Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean. Nature. 2001; 410(6825): 207-12.
Lu H et al. Prevention of the development of preneoplastic lesions, aberrant crypt foci, by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male F344 rats. Oncol Rep. 2001 Nov-Dec;8(6):1341-5.
牛島光保. ツルニンジンの血中テストステロン濃度低下改善作用. Food Style21. 2001; 12(9): 1-2.
Moriguchi T et al. Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. J Neurochem. 2000; 75(6): 2563-73.
Ikeda Y et al. Controlled release of a water-soluble drug, captopril, by a combination of hydrophilic and hydrophobic cyclodextrin derivatives. J Control Release. 2000; 66(2-3): 271-80.
田村恵子ほか. 作業に有効な香りのスクリーニング：8種類の香りの官能評価. 日本味と匂学会誌. 1996; 3(3): 688-691.
Amagase H et al. Dietary rosemary suppresses 7,12-dimethylbenz(a)anthracene binding to rat mammary cell DNA. J Nutr. 1996; 126(5): 1475-80.
杉本尚美ほか. 作業に有効な香りのスクリーニング：官能検査. 日本味と匂学会誌. 1995; 2(3): 511-514.
山下麻乃ほか. 連続照明下ラットの発情周期に対するエリアス(R)ミニの効果. 基礎と臨床. 1995; 29(1): 65-73.
田村恵子ほか. 作業に有効な香りのスクリーニング：官能評価と生理計測. 日本味と匂学会誌. 1995; 2(3): 515-518.
田村恵子ほか. 香りの作業前後での感覚差について. 日本味と匂学会誌. 1994;1(3): 482-485.
Harada Y, Kasuga S. Three-dimensional observation of the Golgi apparatus in the vestibular (Scarpa's) ganglion cell. Acta Otolaryngol Suppl. 1993; 503: 157-9.
Wong BY et al. Modulation of cytochrome P-450IA1-mediated mutagenicity, DNA binding and metabolism of benzo[a]pyrene by Chinese medicinal herbs. Cancer Lett. 1993; 68(1): 75-82.
Wong BY et al. Inhitbition of dexamethasone-induced cytochrome P450-mediated mutagenicity and metabolism of aflatoxin B1 by Chinese medicinal herbs. Eur J Cancer Prev. 1993; 2(4): 351-6.
Sumiyoshi H et al. Heterogenicity of ornithine decarboxylase during mouse colon carcinogenesis and in human colon tumors. Cancer Res. 1991; 51(8): 2069-72.
森永力ほか. ★T8942 特開 平1-252276 腸内有益菌の増殖促進活性成分およびその用途. ビフィズス. 1991; 4(2): 209-211.
Kasuga S. Ultrastructural changes in aging rat tracheal gland. Hiroshima J Med Sci. 1991; 40(2): 63-70.
春日繁男, 原田康夫. 浮遊コラゲン・ゲル培養によるウサギ気管上皮細胞の微細構造. 日気食会報. 1990; 41(4): 283-91.
Kasuga S, Harada Y. Effects of secretory stimulation on the Golgi apparatus and GERL of rat tracheal gland cells. Auris Nasus Larynx. 1990; 17(4): 229-42.
Kasuga S, Harada Y. Three-dimensional observation of the Golgi apparatus in rat tracheal gland during the secretory cycle. Auris Nasus Larynx. 1990; 17(4): 243-58.
春日繁男, 原田康夫. 加齢による気管腺腺房細胞の変化. 医生物走査電顕. 1990;19: 85-87.
Ohtani K et al. Reticuloendothelial System-Activating Polysaccharides from Rhizomes of Panax japonicus. : I. Tochibanan-A and -B. Chem Pharm Bull. 1989; 37(10): 2587-91.
春日繁男, 原田康夫. 気管腺腺房細胞のゴルジ装置. 医生物走査電顕. 1989; 18: 80-82.
Yang CR et al. Blinin, a neoclerodane diterpene from Conyza blinii. Phytochemistry. 1989; 28(11): 3131-4.
隅田利彦ほか. Receptor binding assay法を用いた薬用植物中の活性成分の研究. 薬学雑誌. 1988; 108(5): 450-3.
Mizutani K et al. Tangshenoside I and II from Chuan-Dangshen, the root of Codonopsis tangshen OLIV. Chem Pharm Bull. 1988; 36(7): 2726-9.
Mizutani K et al. Chemical studies on Chinese traditional medicine, dangshen. I. Isolation of(Z)-3- and (E)-2-hexenyl beta-D-glucoside. Chem Pharm Bull. 1988; 36(7): 2689-90.
Mizutani K et al. Amides from Huajiao, pericarps of Zanthoxylum bungeanum MAXIM. Chem Pharm Bull. 1988; 36(7): 2362-5.
Yamaguchi H et al. High-performance liquid chromatographic analysis of acidic saponins of ginseng and related plants. Chem Pharm Bull. 1988; 36(9): 3468-73.
Yamaguchi H et al. Analysys of saponins of wild Panax ginseng. Chem Pharm Bull. 1988; 36(10): 4177-81.
山口啓之ほか. 栽培人参の中性および酸性サポニンの分析. 薬学雑誌. 1988;108(9): 872-5.
隅田利彦ほか. Receptor Binding Assay法を用いた薬用植物中の活性成分の研究 (第2報) Dopamine 2 Receptor. 薬学雑誌. 1988; 105(5): 450-3.
菊池長徳ほか. 末梢血行障害に対するヘプロニカートの臨床使用経験. 診療と新薬. 1988; 25(9): 1850-9.
Ohtani K et al. Sanchinan-A, a reticuloendothelial system activating arabinogalactan from sanchi-ginseng (roots of Panax notoginseng). Planta Med. 1987; 53(2): 166-9.
Sumiyoshi H et al. Effects of a protein-free diet on the rat stomach. Gastroenterology. 1987; 92(4): 1051-9.
Kasuga S et al. A simple method for the observation of cultured rat hepatocytes by scanning electron microscopy. Hiroshima J Med Sci. 1987; 36(2): 169-74.
宇田直人ほか. 7C123WRおよび7C123Wのラット腸管灌流法によるカルシウム腸管吸収試験. 基礎と臨床. 1987; 1(16): 6112-6114.
Kasai R et al. High-performance liquid chromatography of glycosides on a new type of hydroxapatite column. J Chromatogr. 1987; 407: 205-10.
Itakura Y et al. Tannins occurring in the toxic brazilian plant Thiloa glaucocarpa. Toxicon. 1987; 25(12): 1291-300.
Yamaguchi H et al. Application of borate ion-exchange mode high-performance liquid chromatography to separation of glucosides: Saponins of giseng, Sapindus mukurossi GAERTN. And Amemone rivularis BUCH.-HAN. Chem Pharm Bull. 1986; 34(7): 2859-67.
Itakura Y, Komori T. Structure elucidation of two new oligoglycoside sulfates, versicoside B and versicoside C. Liebigs Ann Chem. 1986; 359-73.
Itakura Y, Momori T. Structure elucidation of four new oligoglycoside sulfates. Liebigs Ann Chem. 1986; 499-508.
Tahara E et al. Human epidermal growth factor in gastric carcinoma as a biologic marker of high malignancy. Jpn J Cancer Res. 1986; 77(2): 145-52.
Sumiyoshi H. Effects of vitamin E deficiency on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats. Hiroshima J Med Sci. 1985; 34(3): 363-9.
Sumiyoshi H. Effects of feeding regimen on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats. Hiroshima J Med Sci. 1985; 34(4): 387-93.
Takasugi N et al. Effect of Eleuterococcus senticosus and its components on rectal temperature, body and grip tones, motor coordination, and exploratory and spontaneous movements in acute stressed mice. 生薬学雑誌. 1985; 39(3): 232-7.
Tamai G et al. Isolation of new quinidine metabolites and simultaneous determination of quinidine and metabolites in blood and urine by direct injection HOLC analysis. Chromatographia. 1985; 20(11): 671-6.
Yamamoto M et al. Distribution of collagen types I, III, and V in fibrotic and neoplastic human liver. Acta Pathol Jpn. 1984; 34(1): 77-86.
Sumiyoshi H et al. Effects of gastrin on tumor growth and cyclic nucleotide metabolism in xenotransplantable human gastric and colonic carcinomas in nude mice. Cancer Res. 1984; 44(10): 4276-80.
Sumiyoshi H et al. Secretory component and immunoglobulin in human gastric carcinoma: an immunohistochemical study. Gann. 1984; 75(2): 166-76.
Yamamoto M et al. Distribution of collagen types I and III and basal lamina in human gastric carcinoma: an immunohistochemical and electron microscopic study. Virchows Arch A Pathol Anat Histopathol. 1984; 403(4): 313-22.
Matsuura H et al. Further studies on dammarane-sponins of ginseng roots. Chem Pharm Bull. 1984; 32(3): 1188-92.
Matsuura H et al. Study of red ginseng: New glucoside and a note on the occurrence of maltol. Chem Pharm Bull. 1984; 32(11): 4674-7.
Fusetani N et al. Biological activity of asterosaponins with special reference to structure-activity relationships. J Nat Prod. 1984; 47(6): 997-1002.
山口啓之ほか. 高速液体クロマトグラフィーによる酢酸α-トコフェロール立体異性体の分析. 医薬品研究. 1984; 15(4): 536-40.
原昭ニほか. トリテルペノイドサポニゲンを用いる液・固クロマトグラフィーにおける強成分溶媒の相対強度の図式化. 薬学雑誌. 1983; 103(2): 231-5.
Komori T et al. Isolation and structure of the oligoglycoside sulfates. Liebigs Ann Chem. 1983; 24-36.
Komori T et al. Structures of two newly characterized genuine sapogenins and ab oligoglycoside sulfate. Liebigs Ann Chem. 1983; 37-55.
Itakura Y et al. Steroid oligoglycoside from the starfish Astropecten latespinosus Meissner. Liebigs Ann Chem. 1983; 56-68.
Itakura Y et al. Steroid oligoglycoside from the starfish Astropecten latespinosus [cf.] versicolor sladen, 1 Structural elucidation of a new oligoglycoside sulfate. Liebigs Ann Chem. 1983; 2079-91.
Komori T et al. Steroid Oligoglycoside aus dem Seestern Luidia maculata Muller et Troschel, 1 Die Strukturen eines neuen Aglycosulfats und von zwei neuen Oligoglycosidsulfaten. Liebigs Ann Chem. 1983; 2092-113.
Kasai R et al. Saponins of red ginseng. Chem Pharm Bull. 1983; 31(6): 2120-5.
Matsuura H et al. Further studies of dammarane-saponins of Sanchi-ginseng. Chem Pharm Bull. 1983; 31(7): 2281-7.
Morita T et al. Chemical and morphological study on Chinese Panax japonicus C.A. Meyer (Zhujie-Shen). Chem Pharm Bull. 1983; 31(9): 3205-9.
国弘和雄ほか. 人参サポニゲンのシリカゲル液・固クロマトグラフィーにおける溶出挙動. 分析化学. 1982; 31: 83-7.
Hara S et al. Ternary solvent system design for liquid-solid chromatography. J Chromatography. 1982; 239: 687-94.
Besso H et al. Further studies on dammarane-saponins of American ginseng, roots of Panax quinquefolium L. Chem Pharm Bull. 1982; 30(12): 4534-8.
池田陽一ほか. 精油成分とα-およびβ-シクロデキストリンとの抱接複合体形成. 薬学雑誌. 1982; 102(1): 83-8.
井藤久雄ほか. 我々の研究している腫瘍マーカー－特に胃癌における免疫活性 h.C.G., Lysozyme及びα1-antitripsinについて－. 最新医学. 1982; 37(6): 1226-8.
Tahara E et al. Enhanced effect of gastrin on rat stomach carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine. Cancer Res. 1982; 42(5): 1781-7.
Tahara E et al. Argyrophil cells in early gastric carcinoma: an immunohistochemical and ultrastructural study. J Cancer Res Clin Oncol. 1982; 103(2): 187-202.
Nakagawa S, MatsuoY. Bacteriocin and hemolysin from Streptococcus faecium. Antimicrob Agents Chemother. 1981; 20(4): 542-544.
Zhou J et al. Dammarane-saponins of Sanchi-ginseng, roots of Panax notoginseng (Burk.) F.H. Chen (Araliaceae): Structures of new saponins, notoginsenosides-R1 and -R2, and identification of notoginsenosides-Rg2 and -Rh1. Chem Pharm Bull. 1981; 29(10): 2844-50.
Besso H et al. Ginsenoside-Ra1 and ginsenoside-Ra2, new dammarane-saponins of ginseng roots. Chem Pharm Bull. 1981; 30(7): 2380-5.
Okumura K et al. Tissue distribution and metabolism of drugs VI: Effect of second drugs on pancreatic distribution and insulin-releasing activity of sulfonylureas in perfused rat pancreas. J Pharm Sci. 1980; 69(2): 157-9.
中川静紀, 松尾吉恭. D群連鎖球菌の産生するバクテリオシンに関する研究 1. 数種のバクテリオシンの諸性状. 広島大学医学雑誌. 1979; 27(5): 809-25.
中川静紀, 松尾吉恭. D群連鎖球菌の産生するバクテリオシンに関する研究 2. Streptococcus faeciumのバクテリオシン産生能の種々の処理による除去. 広島大学医学雑誌. 1979; 27(5): 827-36.
中川静紀, 松尾吉恭. D群連鎖球菌の産生するバクテリオシンに関する研究 3. Streptococcus faeciumのバクテリオシンとヘモリジンの産生能の解析. 広島大学医学雑誌. 1979; 27(5): 837-47.
Kobayashi B et al. Differential contribution of oxidative and glycolytic energy to thrombin-induced platelet functions. Thromb Haemost. 1979; 42(2): 655-65.
Besso H et al. High-performance liquid chromatographic determination of ginseng saponin by ultraviolet derivatisation. Planta Med. 1979; 37(11): 226-333.
Saruwatari Y et al. Thin-layer chromatographic determination of panaxadiol and panaxatriol by ultraviolet derivatization. Chem Pharm Bull. 1979; 27(1): 147-51.
Besso H et al. Reactions of 4H-pyran-4-thiones with ammonia, hydrazine, and guanidine. Bull Chem Soc Jpn. 1978; 51(1): 179-81.
Besso H et al. Tautomerism of 4-pyridones. Bull Chem Soc Jpn. 1977; 50(3): 710-2.
Besso H et al. Substituent effects on dissociation constants of trans-3-hydroxy-6-styryl-4-pyrones. Bull Chem Soc Jpn. 1977; 50(8): 2161-3.
Besso H et al. Substituent effects on tautomerism of 4-pyridinethiones. Bull Chem Soc Jpn. 1977; 50(12): 3295-7.
